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2017年
  1. Yoshida, M., Kato, N., Uemura, T., Mizoi, M., Nakamura, M., Saiki, R., Hatano, K., Sato, K., Kakizaki, S., Nakamura, A., Ishii, T., Terao, T., Murayama, Y., Kashiwagi, K., Igarashi, K.: Time dependent transition of the levels of protein-conjugated acrolein (PC-Acro), IL-6 and CRP in plasma during stroke. eNeurologicalSci. 7. 18-24. (2017)

  2. Yoshida, M., Kanzaki, T., Mizoi, M., Nakamura, M., Uemura, T., Mimori, S., Uju, Y., Sekine, K., Ishii, Y., Yoshimi, T., Yasui, R., Yasukawa, A., Sato, M., Okamoto, S., Hisaoka, T., Miura, M., Kusanishi, S., Murakami, K., Nakano, C., Mizuta, Y., Mishima, S., Hayakawa, T., Tsukada, K., Kashiwagi, K., Igarashi, K.: Correlation between brain damage, associated biomarkers, and medication in psychiatric inpatients: A cross-sectional study. Clin. Chim. Acta. 464. 50-56. (2017)

  3. Uemura, T., Suzuki, T., Saiki, R., Dohmae, N., Ito, S., Takahashi, H., Toida, T., Kashiwagi, K., Igarashi, K.: Activation of MMP-9 activity by acrolein in saliva from patients with primary Sjögren’s syndrome and its mechanism. Int. J. Biochem. Cell Biol. 88. 84-91. (2017)

2016年
  1. 坂本明彦, 富取秀行:ポリアミンの酸化分解により産生されるアクロレインの細胞毒性と疾患. ポリアミン 3 (2), 38-46. (2016)

  2. Imamura, M., Higashi, K., Yamaguchi, K., Asakura, K., Furihata, T., Terui, Y., Satake, T., Maegawa, J., Yasumura, K., Ibuki,A., Akase, T., Nishimura, K., Kashiwagi, K., Linhardt, R. J., Igarashi, K., Toida, T.: Polyamines release the let-7b-mediated suppression of initiation codon recognition during the protein synthesis of EXT2. Sci. Rep. 6, 33549 (2016)

  3. Uemura, T., Nakamura, M., Sakamoto, A., Suzuki, T., Dohmae, N., Terui, Y., Tomitori, H., Casero, R. A., Jr., Kashiwagi, K., Igarashi, K.: Decrease in acrolein toxicity based on the decline of polyamine oxidases. Int. J. Biochem. Cell Biol. 79, 151-157 (2016)

  4. Yoshida, T., Sakamoto, A., Terui, Y., Takao, K., Sugita, Y., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.: Effect of spermidine analogues on cell growth of Escherichia coli polyamine requiring mutant MA261. PLoS One. 11, e0159494 (2016)

  5. Sugiyama, S., Ishikawa, S., Tomitori, H., Niiyama, M., Hirose, M., Miyazaki, Y., Higashi, K., Murata, M., Adachi, H., Takano, K., Murakami, S., Inoue, T., Mori, Y., Kashiwagi, K., Igarashi, K., Matsumura, H.: Molecular mechanism underlying promiscuous polyamine recognition by spermidine acetyltransferase. Int. J. Biochem. Cell Biol. 76, 87-97 (2016)

  6. Hori, H., Terui, Y., Nakamoto, C., Iwashita, C., Ochi, A., Watanabe, K., Oshima, T.: Effets of polyamines from Thermus thermophiles, an extreme-thermophilic eubacterium, on tRNA methylation by tRNA (Gm18) methyltransferase (TrmH). J. Biochem. 159 (5). 509-517 (2016)

  7. Uemura, T., Watanabe, K., Ishibashi, M., Saiki, R., Kuni, K., Nishimura, K., Toida, T., Kashiwagi, K., Igarashi, K.: Aggravation of brain infarction through an increase in acrolein production and a decrease in glutathione with aging. Biochem. Biophys. Res. Commun. 473 (2). 630-635 (2016)

  8. Ge, D., Higashi, K., Ito, D., Nagano, K., Ishikawa, R., Terui, Y., Higashi, K., Moribe, K., Linhardt, RJ., Toida, T.: Poly-ion Complex of Chondroitin Sulfate and Spermine and Its Effect on Oral Chondroitin Sulfate Bioavailability. Chem. Pharm. Bull. 64 (5). 390-398 (2016)

  9. Nakamura, M., Uemura, T., Saiki, R., Sakamoto, A., Park, H., Nishimura, K., Terui, Y., Toida, T., Kashiwagi, K., Igarashi, K.: Toxic acrolein production due to Ca2+ influx by the NMDA receptor during stroke. Atherosclerosis. 244, 131-137 (2016)

2015年
  1. 照井祐介:ポリアミンによる蛋白質合成促進, ポリアミン 2 (2), 46-53 (2015)

  2. Hirose, T., Saiki, R., Uemura, T., Suzuki, T., Dohmae, N., Ito, S., Takahashi, H., Ishii, I., Toida, T., Kashiwagi, K., Igarashi, K.: Increase in acrolein-conjugated immunoglobulins in saliva from patients with primary Sjögren's syndrome. Clin. Chim. Acta. 450, 184-189 (2015)

  3. Igarashi, K., Yoshida, M., Waragai, M., Kashiwagi, K.: Evaluation of dementia by acrolein, amyloid-β and creatinine. Clin. Chim. Acta. 450, 56-63 (2015)

  4. Hirose, T., Saiki, R., Yoshizawa, Y., Imamura, M., Higashi, K., Ishii, I., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.: Spermidine and Ca2+, but not Na+, can permeate NMDA receptors consisting of GluN1 and GluN2A or GluN2B in the presence of Mg2+. Biochem. Biophys. Res. Commun. 463, 1190-1195 (2015)

  5. Igarashi, K., Kashiwagi, K.: Modulation of protein synthesis by polyamines. IUBMB Life 67(3), 160-169 (2015)

  6. Sakamoto, A., Terui, Y., Yoshida, T., Yamamoto, T., Suzuki, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.: Three members of polyamine modulon under oxidative stress conditions: two transcription factors (SoxR and EmrR) and a glutathione synthetic enzyme (GshA). PLoS One 10(4), e0124883 (2015)

  7. Yoshida, M., Higashi, K., Kuni, K., Mizoi, M., Saiki, R., Nakamura, M., Waragai, M., Uemura, K., Toida, T., Kashiwagi, K., Igarashi, K. Distinguishing mild cognitive impairment from Alzheimer's disease with acrolein metabolites and creatinine in urine. Clin. Chim. Acta. 441, 115-121 (2015)

  8. Terui, Y., Sakamoto, A., Yoshida, T., Kasahara, T., Tomitori, H., Higashi, K., Igarashi, K., Kashiwagi, K.: Polyamine stimulation of eEF1A synthesis based on the unusual position of a complementary sequence to 18S rRNA in eEF1A mRNA. Amino Acids 47(2), 345-356 (2015)

  9. Igarashi, K., Terui, Y., Kashiwagi, K.: The polyamine modulon: Genes encoding proteins whose synthesis is enhanced by polyamines at the level of translation. In “Polyamines, a universal molecular nexus for growth, survival and specialised metabolism” (Eds. T. Kusano, and H. Suzuki) pp. 131-141, Springer Japan (2015)

  10. Kashiwagi, K., Williams, K., Igarashi, K.: Regulation of N-methyl-D-aspartate receptors by spermine and ifenprodil. In “Polyamines, a universal molecular nexus for growth, survival and specialised metabolism” (Eds. T. Kusano, and H. Suzuki) pp. 243-253, Springer Japan (2015)

  11. 柏木敬子:原核細胞及び真核細胞のポリアミン輸送系の性質とその生理的意義, ポリアミン 2 (1), 2-11 (2015)

  12. 照井祐介:細菌を寄せ付けない!?生物の驚くべき体表面加工, 生物工学 93(6), 352 (2015)

2014年
  1. Sakamoto, A., Terui, Y., Horie, C., Fukui, T., Masuzawa, T., Sugawara, S., Shigeta, K., Shigeta, T., Igarashi, K., Kashiwagi, K.: Antibacterial effects by protruding and recessed shark skin micropatterned surfaces of polyacrylate plate with a shallow groove. FEMS Microbiol. Lett. 361, 10-16 (2014)

  2. Higashi, K., Imamura, M., Fudo, S., Uemura, T., Saiki, R., Hoshino, T., Toida, T., Kashiwagi, K., Igarashi, K.: Identification of functional amino acid residues involved in polyamine and agmatine transport by human organic cation transporter 2. PLoS One. 9, e102234 (2014)

  3. Sugiyama, S., Kashiwagi, K., Kakinouchi, K., Tomitori, H., Kanai, K., Murata, M., Adachi, H., Matsumura, H., Takano, K., Murakami, S., Inoue, T., Mori, Y., Igarashi, K.: Crystallization and preliminary crystallographic studies of PotA, a membrane-associated ATPase of the spermidine-preferential uptake system in Thermotoga maritima. Acta Crystallogr. F70, 738-741 (2014)

  4. Mizoi, M., Yoshida, M., Saiki, R., Waragai, M., Uemura, K., Akatsu, H., Kashiwagi, K., Igarashi, K.: Distinction between mild cognitive impairment and Alzhemer’s disease by CSF amyloid β40 and β42, and protein-conjugated acrolein. Clin. Chim. Acta 430, 150-155 (2014)

  5. Terui, Y., Saroj, S. D., Sakamoto, A., Yoshida, T., Higashi, K., Kurihara, S., Suzuki, H., Toida, T., Kashiwagi, K., Igarashi, K.: Properties of putrescine uptake by PotFGHI and PuuP and their physiological significance in Escherichia coli. Amino Acids 46, 661-670 (2014)

2013年
  1. Hayashi, Y., Sugiyama, H., Suganami, A., Higashi, K., Kashiwagi, K., Igarashi, K., Kawauchi, S.: Prediction of the interaction between spermidine and G-G mismatch containing acceptor stem in tRNAIle: Molecular modeling, density functional theory, and molecular dynamics study. Biochem. Biophys. Res. Commun. 441 (4) 999-1004 (2013)

  2. Saiki, R., Hayashi, D., Ikuo, Y., Nishimura, K., Ishii, I., Kobayashi, K., Chiba, K., Toida, T., Kashiwagi, K., Igarashi, K.: Acrolein stimulates the synthesis of IL-6 and CRP in thrombosis model mice and cultured cells. J. Neurochem. 127, 652-659 (2013)

  3. Kummasook, A., Cooper, C. R. Jr., Sakamoto, A., Terui, Y., Kashiwagi, K., Vanittanakorn, N.: Spermidine is required for morphogenesis in the human pathogenic fungus, Penicillium marneffei. Fungal Genet. Biol. 58-59, 25-32 (2013)

  4. Niiyama, M., Sugiyama, S., Hirose, M., Ishikawa, S., Tomitori, H., Higashi, K., Yamashita, T., Adachi, H., Takano, K., Murakami, S., Murata, M., Inoue, T., Mori, Y., Kashiwagi, K., Matsumura, H., Igarashi, K.: Expression, purification, crystallization, and preliminary crystallographic analysis of spermidine acetyltransferase from Escherichia coli. Acta Crystallogr. F69, 884-887 (2013)

  5. Yamashita, T., Nishimura, K., Saiki, R., Okudaira, H., Tome, M., Higashi, K., Nakamura, M., Terui, Y., Fujiwara, K., Kashiwagi, K., Igarashi, K.: Role of polyamines at the G1/S boundary and G2/M phase of the cell cycle. Int. J. Biochem. Cell Biol. 45, 1042-1050 (2013)

  6. Saiki, R., Yoshizawa, Y., Minarini, A., Milelli, A., Marchetti, C., Tumiatti, V., Toida, T., Kashiwagi, K., Igarashi, K.: In vitro and in vivo evaluation of polymethylene tetraamine derivatives as NMDA receptor channel blockers. Bioorg Med Chem Lett. 23, 3901-3904 (2013)

  7. Kawashima, E., Nakanishi, Y., Terui, Y., Tomitori, H., Kashiowagi, K., Ohba, Y., Kamaike, K.: Synthesis and evaluation of pyrrole polyamide-2’-deoxyguanosine 5’-phosphate hybrid. Nucleosides, Nucleotides Nucleic Acids 32, 196-205 (2013)

  8. Nakamura, M., Tomitori, H., Suzuki, T., Sakamoto, A., Terui, Y., Saiki, R., Dohmae, N., Igarashi, K., Kashiwagi, K.: Inactivation of GAPDH as one mechanism of acrolein toxicity. Biochem. Biophys. Res. Commun. 430, 1265-1271 (2013)

  9. Shiokawa, K., Mishima, T., Yoshida, H., Takai, J., Tsuboshima, K., Soutome, T., Terui, Y., Abe, H., Sakurai, S., Takahashi, T., Tashiro, K., Igarashi, K.: Changes in polyamines levels in Xenopus early embryogenesis. Trends Dev. Biol. 7, 25-31 (2013)

2012年
  1. Sakamoto, A., Terui, Y., Yamamoto, T., Kasahara, T., Nakamura, M., Tomitori, H., Yamamoto, K., Michael, A. J., Igarashi, K., Kashiwagi, K.: Enhanced biofilm formation and/or cell viability by polyamines through stimulation of response regulators UvrY and CpxR in the two-component signal transducing systems, and ribosome recycling factor. Int. J. Biochem. Cell Biol. 44, 1877-1886 (2012)

  2. Tomitori, H., Suganami, A., Saiki, R., Mizuno, S., Yoshizawa, Y., Masuko, T., Tamura, Y., Nishimura, K., Toida, T., Williams, K., Kashiwagi, K., Igarashi, K.: Structural change of R domain heterodimer of NMDA receptor GluN1 and GluN2B through binding of spermine and ifenprodil. J. Pharmacol. Exp. Ther. 343, 82-90 (2012)

  3. Waragai, M., Yoshida, M., Mizoi, M., Saiki, R., Kashiwagi, K., Takagi, K., Arai, H., Tashiro, J., Hashimoto, M., Iwai, N., Uemura, K., Igarashi, K.: Increased protein-conjugated acrolein and amyloid-β40/42 ratio in plasma of patients with mild cognitive impairment and Alzheimer’s disease. J. Alzheimer’s Dis. 32, 33-41 (2012)

  4. Yoshida, M., Mikami, T., Higashi, K., Saiki, R., Mizoi, M., Fukuda, K., Nakamura, T., Ishii, I., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., Igarashi, K.: Inverse correlation between stroke and urinary 3-hydroxypropyl mercapturic acid, an acrolein-glutathione metabolite. Clin. Chim. Acta 413, 753-759 (2012)

  5. Tomitori, H., Nakamura, M., Sakamoto, A., Terui, Y., Yoshida, M., Igarashi, K., Kashiwagi, K.: Augmented glutathione synthesis decreases acrolein toxicity. Biochem. Biophys. Res. Commun. 418, 110-115 (2012)

  6. Terui, Y., Akiyama, M., Sakamoto, A., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.: Increase in cell viability by polyamines through stimulation of the synthesis of ppGpp regulatory protein and ω protein of RNA polymerase in Escherichia coli. Int. J. Biochem. Cell Biol. 44, 412-422 (2012)

  7. Masuko, T., Suzuki, T., Miyake, M., Kusama-Eguchi, K., Kizawa, Y., Tomono, K., Kashiwagi, K., Igarashi, K., Kusama, T.: Antagonism of NMDA receptors by butanesulfonyl-homospermine guanidine and neuroprotective effects in in vitro and in vivo. Neurosci Lett. 506, 251-255 (2012)

  8. Tomitori, H., Kashiwagi, K., Igarashi, K.: Structure and function of polyamine-amino acid antiporters CadB and PotE in Escherichia coli. Amino Acids, 42, 733-740 (2012)

2011年
  1. Igarashi, K., Kashiwagi, K.: Protein-conjugated acrolein as a biochemical marker of brain infarction. Mol. Nutr. Food Res. 55, 1332-1341 (2011)

  2. Igarashi, K., Kashiwagi, K.: Characterization of genes for polyamine modulon. Methods Mol. Biol. 720, 51-65 (2011)

  3. Oshima, T., Moriya, T., Terui, Y.: Identification, chemical synthesis and biological functions of unusual polyamines produced by extreme thermophiles. Methods Mol. Biol. 720, 81-111 (2011)

  4. Kashiwagi, K., Igarashi, K.: Identification and assays of polyamine transport systems in Escherichia coli and Saccharomyces cerevisiae. Methods Mol. Biol. 720, 295-308 (2011)

  5. Igarashi, K., Kashiwagi, K.: Use of polyamine metabolites as markers for stroke and renal failure. Methods Mol. Biol. 720, 395-408 (2011)

  6. Yamamichi, S., Jinno, Y., Haraya, N., Oyoshi, T., Tomitori, H., Kashiwagi, K., Yamanaka, M.: Separation of proteins using supramolecular gel electrophoresis. Chem. Commun. 47, 10344-10346 (2011)

  7. Yoshida, M., Mizoi, M., Saiki, R., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Kashiwado, K., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Tomitori, H., Kashiwagi, K., Igarashi, K.: Relationship between metabolic disorders and relative risk values of brain infarction estimated by protein-conjugated acrolein, IL-6 and CRP together with age. Clin. Chim. Acta 412, 339-342 (2011)

  8. Saiki, R., Park, H., Ishii, I., Yoshida, M., Nishimura, K., Toida, T., Tatsukawa, H., Kojima, S., Ikeguchi, Y., Pegg, A. E., Kashiwagi, K., Igarashi, K.: Brain infarction correlates more closely with acrolein than with reactive oxygen species. Biochem. Biophys. Res. Commun. 404, 1044-1049 (2011)

  9. Kawashima, E., Ohba, Y., Terui, Y., Kamaike, K.: Synthesis and evaluation of oligonucleotide-conjugated pyrrolepolyamide-2’-deoxyguanosine hybrids as novel gene expression control compounds. Nucleosides, Nucleotides Nucleic Acids 30, 850-872 (2011)

  10. Ohnuma, M., Ganbe, T., Terui, Y., Niitsu, M., Sato, T., Tanaka, N., Tamakoshi, M., Samejima, K., Kumasaka, T., Oshima, T.: Crystal structures and enzymatic properties of a triamine/ agmatine aminopropyltransferase from Thermus thermophilus. J. Mol. Biol. 408, 971-986 (2011)

  11. Moriya, T., Hikota, T., Yumoto, I., Ito, T., Terui, Y., Yamagishi, A., Oshima, T.: Calditerricola satsumensis gen. nov., sp. nov. and C. yamamurae sp. nov., extreme thermophiles isolated from a high temperature compost. Int. J. Sys. Evol. Microbiol. 61, 631-636 (2011)

  12. 五十嵐一衛,柏木敬子:細胞増殖必須因子ポリアミンと代謝物アクロレインの生理作用と臨床応用.化学と生物,49, 32-39 (2011)

2010年
  1. Higashi, K., Sakamaki, Y., Herai, E., Demizu, R., Uemura, T.m Saroj, S. D., Terui, Y., Nishimura, K., Toida, T., Kashiwagi, K., Igarashi, K.: Identification and functions of amino acid residues in PotB and PotC involved in spermidine uptake activity. J. Biol. Chem. 285, 39061-39069 (2010)

  2. Terui, Y., Tabei, Y., Akiyama, M., Higashi, K., Tomitori, H., Yamamoto, K., Ishihama, A., Igarashi, K., Kashiwagi, K.: Ribosome modulation factor, an important protein for cell viability encoded by the polyamine modulon. J. Biol. Chem. 285, 28698-28707 (2010)

  3. Igarashi, K., Kashiwagi, K.: Modulation of cellular function by polyamines. Int. J. Biochem. Cell Biol. 42, 39-51 (2010)

  4. Yoshida, M., Higashi, K., Kobayashi, E., Saeki, N., Wakui, K., Kusaka, T., Takizawa, H., Suzuki, N., Fukuda, K., Nakamura, T., Watanabe, S., Tada, K., Machi, Y., Mizoi, M., Toida, T., Kanzaki, T., Tomitori, H., Kashiwagi, K., Igarashi, K.: Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP. Atherosclerosis 211, 475-479 (2010)

  5. Igarashi, K., Kashiwagi, K.: Characteristics of cellular polyamine transport in prokaryotes and eukaryotes. Plant Physiol. Biochem. 48, 506-512 (2010)

  6. Higashi, K., Yoshida, M., Igarashi, A., Ito, K., Wada, Y., Murakami, S., Kobayashi, D., Nakano, M., Sohda, M., Nakajima, T., Narita, I., Toida, T., Kashiwagi, K., Igarashi, K.: Intense correlation between protein-conjugated acrolein and primary Sjögren's syndrome. Clin. Chim. Acta, 411, 359-363 (2010)

  7. Yoshida, M., Higashi, K., Jin, L., Machi, Y., Suzuki, T., Masuda, A., Dohmae, N., Suganami, A., Tamura, Y., Nishimura, K., Toida, T., Tomitori, H., Kashiwagi, K., Igarashi, K.: Identification of acrolein-conjugated protein in plasma of patients with brain infarction. Biochem. Biophys. Res. Commun. 391, 1234-1239 (2010)

  8. Morimoto, N., Fukuda, W., Nakajima, N., Masuda, T., Terui, Y., Kanai, T., Oshima, T., Imanaka, T., Fujiwara, S.: Dual biosynthesis pathway for longer-chain polyamines in the hyperthermophilic archaeon Thermococcus kodakarensis. J. Bacteriol. 192, 4991-5001 (2010)

  9. Kawashima, E., Ohba, Y., Terui, Y., Kamaike, K.: Design, synthesis and analysis of minor groove binder pyrrolepolyamide-2’-deoxyguanosine hybrids. J. Nucleic Acids 2010, pii.235240. (2010)

  10. 照井祐介:結核菌はなぜホストの中で長く生き延びられるのか.ファルマシア,46, 263-264 (2010)



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